Wen-Xing Ding Selected Research

leupeptin

1/2021	The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB.
1/2016	Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice.

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Wen-Xing Ding Research Topics

Disease

17	Neoplasms (Cancer) 01/2022 - 08/2002
13	Non-alcoholic Fatty Liver Disease 05/2022 - 01/2017
13	Liver Diseases (Liver Disease) 01/2022 - 09/2003
13	Necrosis 12/2019 - 01/2012
10	Mitochondrial Diseases (Mitochondrial Disease) 06/2022 - 09/2003
10	Inflammation (Inflammations) 01/2022 - 05/2013
9	Fatty Liver 01/2021 - 01/2010
8	Acute Liver Failure (Fulminant Hepatic Failure) 12/2021 - 10/2004
7	Ischemia 01/2022 - 09/2003
6	Carcinogenesis 01/2022 - 01/2019
6	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 08/2002
6	Liver Failure 01/2022 - 09/2003
6	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2019 - 09/2003
5	Obesity 01/2021 - 10/2013
5	Hepatitis 01/2020 - 09/2003
5	Starvation 01/2018 - 02/2008
4	Alcoholic Fatty Liver 03/2022 - 12/2012
4	Pancreatitis 01/2022 - 11/2019
4	Fibrosis (Cirrhosis) 01/2022 - 12/2012
4	Colonic Neoplasms (Colon Cancer) 09/2013 - 02/2007
3	Chemical and Drug Induced Liver Injury 03/2022 - 12/2012
3	Dyslipidemias (Dyslipidemia) 01/2022 - 10/2013
2	Liver Neoplasms (Liver Cancer) 03/2022 - 12/2012
2	Tuberous Sclerosis (Bourneville's Disease) 01/2022 - 01/2020
2	Hypercholesterolemia 01/2021 - 01/2020
2	Edema (Dropsy) 01/2020 - 11/2019
2	Hepatomegaly 01/2019 - 01/2017
2	Insulin Resistance 01/2019 - 01/2018
2	Poisoning 01/2019 - 01/2019
2	Atherosclerosis 01/2018 - 02/2015
1	Bites and Stings (Sting) 06/2022
1	Leukemia 01/2022
1	Chronic Pancreatitis 01/2022
1	Lymphoma (Lymphomas) 01/2022
1	Metaplasia 01/2022

Drug/Important Bio-Agent (IBA)

19	Acetaminophen (Paracetamol)FDA LinkGeneric 12/2021 - 01/2012
16	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2003
6	Bile Acids and Salts (Bile Acids)IBA 03/2022 - 02/2014
6	UbiquitinIBA 01/2022 - 03/2007
6	CholesterolIBA 01/2021 - 10/2013
5	Transcription Factors (Transcription Factor)IBA 01/2022 - 11/2019
5	LipidsIBA 01/2022 - 01/2017
5	Phosphotransferases (Kinase)IBA 01/2022 - 04/2016
5	Ethanol (Ethyl Alcohol)IBA 01/2022 - 01/2014
5	Pharmaceutical PreparationsIBA 12/2021 - 07/2012
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 11/2011
5	Proteasome InhibitorsIBA 09/2013 - 03/2007
4	Insulin (Novolin)FDA Link 01/2021 - 11/2017
4	CaspasesIBA 10/2016 - 09/2003
4	Proteasome Endopeptidase Complex (Proteasome)IBA 04/2016 - 03/2007
3	Protein Kinases (Protein Kinase)IBA 01/2022 - 12/2013
3	Beclin-1IBA 01/2021 - 05/2011
3	Glutathione (Reduced Glutathione)IBA 01/2018 - 08/2002
3	Protein AggregatesIBA 12/2012 - 02/2007
2	Mitochondrial DNA (mtDNA)IBA 06/2022 - 10/2017
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2022 - 01/2022
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2022 - 01/2021
2	Amylases FDA Link 01/2022 - 01/2020
2	X-Box Binding Protein 1IBA 01/2022 - 01/2021
2	leupeptinIBA 01/2021 - 01/2016
2	Indicators and Reagents (Reagents)IBA 01/2021 - 11/2010
2	SolutionsIBA 01/2021 - 02/2011
2	SaltsIBA 01/2021 - 02/2011
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2021 - 03/2016
2	Messenger RNA (mRNA)IBA 01/2021 - 11/2017
2	CytokinesIBA 01/2020 - 01/2020
2	Sirolimus (Rapamycin)FDA Link 01/2020 - 01/2019
2	Lipase (Acid Lipase)FDA Link 01/2020 - 01/2017
2	Oxidants (Oxidizing Agents)IBA 12/2019 - 12/2013
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 01/2018
2	Vinyl Chloride (Chloroethylene)IBA 01/2019 - 01/2018
2	Alanine Transaminase (SGPT)IBA 01/2019 - 01/2016
2	EnzymesIBA 09/2018 - 01/2018
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2016 - 10/2004
2	Chloroquine (Aralen)FDA LinkGeneric 01/2016 - 07/2009
2	Small Interfering RNA (siRNA)IBA 01/2016 - 08/2012
2	Metformin (Glucophage)FDA LinkGeneric 02/2015 - 01/2015
2	Death Domain ReceptorsIBA 07/2010 - 09/2003
1	RNA (Ribonucleic Acid)IBA 06/2022
1	InterferonsIBA 06/2022
1	VLDL LipoproteinsIBA 05/2022
1	Caspase 3 (Caspase-3)IBA 01/2022
1	Keratin-19 (Keratin 19)IBA 01/2022
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2022
1	Lipoproteins (Lipoprotein)IBA 01/2022
1	Oxidoreductases (Dehydrogenase)IBA 01/2022
1	GlypicansIBA 01/2022
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2022
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2022
1	trypsinogen activation peptideIBA 01/2022
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2022
1	Glutamate-Cysteine LigaseIBA 01/2022
1	Peroxidase (Myeloperoxidase)IBA 01/2022
1	FatsIBA 01/2022
1	NAD (NADH)IBA 01/2022
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 01/2022

Therapy/Procedure

6	Therapeutics 09/2014 - 10/2004
3	Liver Transplantation 01/2022 - 08/2008
3	Drug Therapy (Chemotherapy) 08/2012 - 08/2009
1	Transplantation 01/2022